[Disorders of the membrane skeleton of erythrocytes in hereditary spherocytosis and elliptocytosis: significance of the molecular defect for pathogenesis and clinical severity].

Abstract excerpt

During recent years an increasing number of inherited variants of erythrocyte membrane proteins and defects of the membrane skeleton could be described. Mostly these defects explain the pathogenesis of hemolytic anemias due to erythrocyte membrane defects. For hereditary spherocytosis and ellipto...

Topics

• Actins
• Child
• Elliptocytosis, Hereditary
• Erythrocyte Membrane
• Humans
• Mutation
• Polymerase Chain Reaction
• Spectrin
• Spherocytosis, Hereditary