Article
Genetic susceptibility to thrombosis.
Current atherosclerosis reports - 1 May 2006
Luyendyk James P, Tilley Rachel E, Mackman Nigel
Abstract excerpt
Thrombosis is associated with atherosclerosis, sepsis, cancer, and numerous other inflammatory diseases. Complications of thrombosis, such as myocardial infarction, stroke, and venous thromboembolism, contribute significantly to morbidity and mortality. Susceptibility to thrombosis is conferred by both genetic and environmental factors. Tissue factor is the primary cellular initiator of blood coagulation and is a...
Topics
- Cytokines
- Genetic Predisposition to Disease
- Humans
- Inflammation
- Lipopolysaccharide Receptors
- Polymorphism, Genetic
- Thromboplastin
- Thrombosis