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Article

Developmental autoregulation of calcium currents in mammalian central neurones.

Neuroreport - 3 Oct 1994

de Desarmenien M G, Dayanithi G, Tapia-Arancibia L, Widmer H

Abstract excerpt

The influence of calcium currents expressed at early stages on the subsequent development of calcium currents was studied in embryonic rat hypothalamic neurones in culture. Voltage-activated calcium currents and spontaneous fluctuations of intracellular free calcium concentration ([Ca2+]i) were monitored. Acute application of nickel chloride (0.1 mM) to 6- to 7-day-old cultures strongly reduced calcium currents...

Topics

Animals
Calcium
Calcium Channels
Cells, Cultured
Electrophysiology
Fura-2
Homeostasis
Neurons
Nickel
Patch-Clamp Techniques
Phenotype
Rats

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Identifiers

PMID: 7841382
DOI: 10.1097/00001756-199410000-00028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7841382-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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