Article
Q- and L-type calcium channels control the development of calbindin phenotype in hippocampal pyramidal neurons in vitro.
The European journal of neuroscience - 1 Jun 2000
Boukhaddaoui H, Sieso V, Scamps F, Vigues S, Roig A, Valmier J
Abstract excerpt
Cultured immature hippocampal neurons from embryonic 17-day-old rats were used to explore activity-dependent regulation of neuronal phenotype differentiation in the developing hippocampus. The calbindin-D28k phenotype of the pyramidal neurons appeared during the first 6 days in culture, and was expressed by 12% of the cells on day 6. Daily stimulation with 50 mM KCl during the first 5 days in vitro increased the...
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