Vesicular stomatitis virus transcription inhibited by purified MxA protein.

doi:10.1016/s0042-6822(95)80071-9

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Article

Vesicular stomatitis virus transcription inhibited by purified MxA protein.

Virology - 10 Jan 1995

Schwemmle M, Weining K C, Richter M F, Schumacher B, Staeheli P

Abstract excerpt

MxA is a GTPase encoded by an interferon-inducible human gene. Its constitutive expression renders transfected mammalian cells resistant to infections with several different RNA viruses, including vesicular stomatitis virus (VSV). Differences in viral RNA levels of VSV-infected cells either expre...

Topics

Animals
Antiviral Agents
Cell Line
Cricetinae
GTP Phosphohydrolases
GTP-Binding Proteins
Guanosine Triphosphate
Histidine
Hydrolysis
Mutation
Myxovirus Resistance Proteins
Nucleotides
Proteins
Transcription, Genetic
Vesicular stomatitis Indiana virus

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