Quantitative comparison of FMR1 gene expression in normal and premutation alleles.

Article

Quantitative comparison of FMR1 gene expression in normal and premutation alleles.

American journal of human genetics - 1 Jan 1995

Feng Y, Lakkis L, Devys D, Warren S T

Abstract excerpt

We report studies on FMR1 gene expression in cells derived from male premutation carriers. Transcription of FMR1 genes with CGG-repeat lengths within the premutation range was demonstrated to be normal. Repeat lengths are faithfully transcribed into FMR1 mRNAs, which have steady-state levels, as...

Topics

Alleles
Base Sequence
Female
Fragile X Mental Retardation Protein
Fragile X Syndrome
Gene Expression
Half-Life
Humans
Male
Minisatellite Repeats
Molecular Sequence Data
Nerve Tissue Proteins
RNA, Messenger
RNA-Binding Proteins

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