Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of the FMR1 gene.

Cytogenetic and genome research - 1 Jan 2003

Tassone F, Hagerman P J

Abstract excerpt

Fragile X syndrome is a trinucleotide repeat disorder in which a (CGG)n element located within the 5' untranslated region of the Fragile X Mental Retardation 1 (FMR1) gene expands to more than 200 copies (full mutation) and becomes hypermethylated. Such expansions are accompanied by the failure to produce FMR1 protein (FMRP), resulting in the fragile X phenotype. For smaller (premutation) expansions...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Trinucleotide Repeat Expansion
Share to DNA Methylation
Share to Fragile X Mental Retardation Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fragile X Syndrome

Share to Gene Expression Regulation

Share to Nerve Tissue Proteins

Share to RNA-Binding Proteins

Share to Sex Factors

Source

Identifiers

PMID: 14526172
DOI: 10.1159/000072846

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of the FMR1 gene.PMID 14526172Read ↗

Transcription of the FMR1 gene in individuals with fragile X syndrome.Semantic proximity Read ↗

Fragile X males with unmethylated, full mutation trinucleotide repeat expansions have elevated levels of FMR1 messenger RNA.Semantic proximity Read ↗

Examination of FMR1 transcript and protein levels among 74 premutation carriers.Semantic proximity Read ↗

A fragile balance: FMR1 expression levels.Semantic proximity Read ↗

A majority of fragile X males with methylated, full mutation alleles have significant levels of FMR1 messenger RNA.Semantic proximity Read ↗

Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation.Semantic proximity Read ↗

Fragile X mental retardation protein: past, present and future.Semantic proximity Read ↗

Elevated FMR1 mRNA in premutation carriers is due to increased transcription.Semantic proximity Read ↗

Quantitative comparison of FMR1 gene expression in normal and premutation alleles.Semantic proximity Read ↗

Epigenetic analysis reveals a euchromatic configuration in the FMR1 unmethylated full mutations.Semantic proximity Read ↗

Normal phenotype in two brothers with a full FMR1 mutation.Semantic proximity Read ↗

FMR1 Protein Expression Correlates with Intelligence Quotient in Both Peripheral Blood Mononuclear Cells and Fibroblasts from Individuals with an FMR1 Mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.