Differential responses of phenotypically distinct rat trophoblast cell lines to MHC class I antigen-inducing cytokines.

doi:10.1016/s0143-4004(05)80405-9

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Article

Differential responses of phenotypically distinct rat trophoblast cell lines to MHC class I antigen-inducing cytokines.

Placenta - 1 Sept 1994

Roby K F, Hamlin G P, Soares M J, Hunt J S

Abstract excerpt

Phenotypically distinct rat trophoblast cell lines, the Rcho-1 and R8RP.3 cells, were compared for their responses to cytokines known to induce major histocompatibility (MHC) class I antigens, tumour necrosis factor (TNF), transforming growth factor-beta (TGF-beta), and interferon-gamma (IFN-gamma). Cell enzyme immunosorbent assays and flow cytometry experiments showed that only IFN-gamma could induce RT1 class I...

Topics

Animals
Blotting, Northern
Cell Adhesion
Cell Line
Cytokines
Enzyme-Linked Immunosorbent Assay
Female
Flow Cytometry
Histocompatibility Antigens Class I
Interferon-gamma
Mitochondria

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Pregnancy

RNA, Messenger

Rats

Transcription, Genetic

Transforming Growth Factor beta

Trophoblasts

Source

Open in PubMed

Identifiers

PMID: 7824444
DOI: 10.1016/s0143-4004(05)80405-9

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7824444-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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