Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transfected trophoblast-derived human cells can express a single HLA class I allelic product.

Tissue antigens - 1 Feb 1991

Boucraut J, Hakem R, Gauthier A, Fauchet R, Le Bouteiller P

Abstract excerpt

The human trophoblast-derived JAR cell line, that does not express polymorphic HLA class I antigens even after IFN induction, can be stably transfected by genomic clones encoding the entire HLA-A2, -A3 and -B7 alpha-chain genes. The transfected genes were expressed at the cell surface in association with endogenous beta 2-microglobulin (shown by FCM analysis) as a single allelic product without reexpression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Expression Regulation, Neoplastic
Share to HLA Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Pregnancy

Share to Recombinant Proteins

Share to Transcription Factors

Share to Transfection

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 1905426
DOI: 10.1111/j.1399-0039.1991.tb01850.x

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transfected trophoblast-derived human cells can express a single HLA class I allelic product.PMID 1905426Read ↗

Molecular studies of trophoblast HLA-G: polymorphism, isoforms, imprinting and expression in preimplantation embryo.Semantic proximity Read ↗

Absence of imprinting of HLA class Ia genes leads to co-expression of biparental alleles on term human trophoblast cells upon IFN-gamma induction.Semantic proximity Read ↗

The soluble pool of HLA-G produced by human trophoblasts does not include detectable levels of the intron 4-containing HLA-G5 and HLA-G6 isoformsSemantic proximity Read ↗

A Class I Antigen, HLA-G, Expressed in Human TrophoblastsSemantic proximity Read ↗

Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA Class I molecule.Semantic proximity Read ↗

An alternatively spliced form of HLA-G mRNA in human trophoblasts and evidence for the presence of HLA-G transcript in adult lymphocytes.Semantic proximity Read ↗

Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti‐HLA antibodiesSemantic proximity Read ↗

Th1- and Th2-like cytokine production by first trimester decidual large granular lymphocytes is influenced by HLA-G and HLA-ESemantic proximity Read ↗

Evidence for the expression of HLAA-C class I mRNA and protein by human first trimester trophoblastSemantic proximity Read ↗

IL-10 selectively induces HLA-G expression in human trophoblasts and monocytesSemantic proximity Read ↗

Differential responses of phenotypically distinct rat trophoblast cell lines to MHC class I antigen-inducing cytokines.Semantic proximity Read ↗

HLA-G Transactivation by cAMP-response Element-binding Protein (CREB)Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.