Article
Late-onset mitochondrial myopathy.
Annals of neurology - 1 Jan 1995
Johnston W, Karpati G, Carpenter S, Arnold D, Shoubridge E A
Abstract excerpt
In the majority of patients with mitochondrial encephalomyopathies, signs and symptoms appear in the first three decades of life. Here we report on a group of 9 older patients (> 69 years old) with late-onset skeletal myopathy characterized by focal accumulations of deleted mitochondrial DNAs (mt...
Topics
- Aged
- Aging
- Biopsy
- DNA, Mitochondrial
- Female
- Humans
- Magnetic Resonance Spectroscopy
- Male
- Mitochondria
- Mitochondrial Myopathies
- Muscle, Skeletal
- Phenotype
- Phosphates
- Phosphocreatine
- Retrospective Studies
- Sequence Deletion