Article
Antiviral capsid-binding compounds can inhibit the adsorption of minor receptor rhinoviruses.
Antiviral research - 1 Sept 1994
Dewindt B, van Eemeren K, Andries K
Abstract excerpt
The effect of four structurally diverse capsid-binding compounds on the adsorption of seven human rhinoviruses (HRV), representative for both receptor and antiviral groupings was studied using infective center assays. Antiviral compounds studied included a pyridazinamine (R 61837), an isoxazole (WIN 51711), a flavan (4',6-dichloroflavan) and a chalcone (Ro-09410). Minor receptor viruses studied were HRV 1A, HRV 2...
Topics
- Adsorption
- Antiviral Agents
- Capsid
- Chalcone
- Chalcones
- Flavonoids
- HeLa Cells
- Humans
- Isoxazoles
- Mutation
- Protein Conformation
- Pyridazines
