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Article

Role of genotype in the adaptation of the brain dopamine system to stress.

Neuroscience and biobehavioral reviews - 1 Jan 1990

Puglisi-Allegra S, Kempf E, Cabib S

Abstract excerpt

Behavioral and biochemical analysis of the effects of stress on brain dopamine (DA) functioning in two inbred strains of mice reveals opposite patterns of adaptation to chronic stress. Chronically stressed mice of the C57BL/6 (C57) strain are characterized by hypersensitive mesolimbic DA autoreceptors and by a dramatic increase of D1/D2 DA receptor ratio (possibly postsynaptic) in the nucleus accumbens septi...

Topics

Adaptation, Psychological
Animals
Brain
Dopamine
Genotype
Humans
Stress, Psychological

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2287492
DOI: 10.1016/s0149-7634(05)80078-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2287492-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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