Genotype-dependent effects of chronic stress on apomorphine-induced alterations of striatal and mesolimbic dopamine metabolism.

doi:10.1016/0006-8993(91)91002-i

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Article

Genotype-dependent effects of chronic stress on apomorphine-induced alterations of striatal and mesolimbic dopamine metabolism.

Brain research - 22 Feb 1991

Cabib S, Puglisi-Allegra S

Abstract excerpt

After 10 daily consecutive restraint experiences, DBA/2 (DBA) mice showed an increase of climbing behavior after injection of 0.25 mg/kg of the dopamine (DA) agonist apomorphine (APO), while no changes were observed following vehicle or 1 mg/kg of APO. By contrast, chronically stressed C57BL/6 (C...

Topics

Animals
Apomorphine
Behavior, Animal
Chronic Disease
Corpus Striatum
Dopamine
Genotype
Limbic System
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Stress, Physiological

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