Article
Assembly of alcohol oxidase in peroxisomes of the yeast Hansenula polymorpha requires the cofactor flavin adenine dinucleotide.
Molecular biology of the cell - 1 Aug 1994
Evers M E, Titorenko V I, van der Klei I J, Harder W, Veenhuis M
Abstract excerpt
The peroxisomal flavoprotein alcohol oxidase (AO) is an octamer (600 kDa) consisting of eight identical subunits, each of which contains one flavin adenine dinucleotide molecule as a cofactor. Studies on a riboflavin (Rf) auxotrophic mutant of the yeast Hansenula polymorpha revealed that limitati...
Topics
- Alcohol Oxidoreductases
- Biological Transport, Active
- Enzyme Activation
- Flavin-Adenine Dinucleotide
- Immunohistochemistry
- Microbodies
- Microscopy, Electron
- Molecular Chaperones
- Mutation
- Pichia
- Protein Conformation
- Riboflavin