Article
TAP polymorphism in patients with Behçet's disease.
Annals of the rheumatic diseases - 1 May 1995
González-Escribano M F, Morales J, García-Lozano J R, Castillo M J, Sánchez-Román J, Núñez-Roldán A, Sánchez B
Abstract excerpt
OBJECTIVE: To determine if susceptibility to Behçet's disease (BD) is associated with polymorphism of HLA-DRB1, HLA-DQB1, DQB1, and TAP1 and TAP2 genes. METHODS: Fifty eight Spanish BD patients and 116 ethnically matched unrelated healthy subjects were typed at the HLA-DRB1 and HLA-DQB1 loci using polymerase chain reaction/sequence specific oligotyping (PCR/SSO). TAP1 and TAP2 alleles were assigned using...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Adult
- Alleles
- Behcet Syndrome
- Disease Susceptibility
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- HLA-DR Antigens