Article
Definition of the bleeding tendency in factor XI-deficient kindreds--a clinical and laboratory study.
Thrombosis and haemostasis - 1 Feb 1995
Bolton-Maggs P H, Patterson D A, Wensley R T, Tuddenham E G
Abstract excerpt
Individuals with severe factor XI deficiency are prone to excessive bleeding after injury or surgery, but the existence of a haemorrhagic tendency in partial factor XI deficiency is controversial. In this study, 172 members of 30 kindreds (20 non-Jewish) transmitting factor XI deficiency in North West England were interviewed and a bleeding history questionnaire completed. Blood was taken for coagulation assays....
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