Article
Definition of the bleeding tendency in factor XI-deficient kindreds--a clinical and laboratory study.
Thrombosis and haemostasis - 1 Feb 1995
Bolton-Maggs P H, Patterson D A, Wensley R T, Tuddenham E G
Abstract excerpt
Individuals with severe factor XI deficiency are prone to excessive bleeding after injury or surgery, but the existence of a haemorrhagic tendency in partial factor XI deficiency is controversial. In this study, 172 members of 30 kindreds (20 non-Jewish) transmitting factor XI deficiency in North...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Bleeding Time
- Case-Control Studies
- Child
- Child, Preschool
- England
- Factor VIII
- Factor XI Deficiency
- Female
- Genes, Recessive
- Genotype
- Hemorrhage
- Heterozygote
- History of Medicine
- Humans