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Myelin/oligodendrocyte glycoprotein is a unique member of the immunoglobulin superfamily

1 Sept 1992

Abstract excerpt

Myelin/oligodendrocyte glycoprotein (MOG) is a primary target autoantigen in experimental autoimmune encephalomyelitis, a widely used animal model for autoimmune demyelinating diseases such as multiple sclerosis. We have isolated several rat MOG cDNAs and confirmed their identity by comparison with MOG N-terminal peptide sequence. As expected, MOG mRNA expression is CNS-specific and peaks during active...

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PMID: 1453482
DOI: 10.1002/jnr.490330123

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