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Article

Genome-wide loss of maternal alleles in a nephrogenic rest and Wilms' tumour from a BWS patient.

Human genetics - 1 Jun 1995

Hoban P R, Heighway J, White G R, Baker B, Gardner J, Birch J M, Morris-Jones P, Kelsey A M

Abstract excerpt

A patient with Beckwith-Wiedemann syndrome (BWS) presented with Wilms' tumour. Examination of the nephrectomy specimen showed, in addition to the tumour, the presence of nephrogenic rests. Nephrogenic rests are thought to be precursor lesions from which a Wilms' tumour may develop. A molecular analysis examining the loss of constitutional heterozygosity (LOCH), initially for chromosome 11, was performed on...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 7789950
DOI: 10.1007/BF00209482

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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