Article
[Genetic diagnosis of diabetes mellitus].
Rinsho byori. The Japanese journal of clinical pathology - 1 May 1995
Suzuki S
Abstract excerpt
NIDDM is likely to have a major genetic component in view of the different prevalence between ethnic groups, the familial clustering, and the high concordance in monozygotic twins. Linkage analysis of extended pedigrees of patients with maturity-onset diabetes of the young (MODY) identified the glucokinase gene mutations. Specific phenotypes have also led to the discovery of the insulin gene mutations in patients...
Topics
- DNA, Mitochondrial
- Diabetes Mellitus, Type 2
- Glucokinase
- Humans
- Insulin
- Mutation
- Receptor, Insulin