Article
[Genetic background of diabetes mellitus type 2].
Nederlands tijdschrift voor geneeskunde - 1 Jan 2009
Wijmenga Cisca, van Haeften Timon W, Hofker Marten H
Abstract excerpt
Diabetes mellitus type 2 (DM2) is the most prevalent form of diabetes, and is caused by a combination of genetic and non-genetic factors. Genome-wide association studies have led to the identification of 20 genetic risk factors for DM2, for which the actual causal mutations are not yet known. Nevertheless, some of the genes connected with diabetes suggest that the pancreatic beta cell plays a central role in the...
Topics
- Diabetes Mellitus, Type 2
- Genetic Predisposition to Disease
- Humans
- Mutation
- Prognosis
- Risk Factors
- Transcription Factors