Article
Ultrastructural effects of diclazuril against Toxoplasma gondii and investigation of a diclazuril-resistant mutant.
The Journal of parasitology - 1 Jun 1995
Lindsay D S, Rippey N S, Toivio-Kinnucan M A, Blagburn B L
Abstract excerpt
Diclazuril is an anticoccidial that inhibits tachyzoite production of the RH strain of Toxoplasma gondii by > 97% at a concentration of 0.005 micrograms/ml. The effects of 1.0 microgram/ml diclazuril on the development of 3 strains (RH and 2 tissue cyst formers, GT-1, and WTD-3) of T. gondii in v...
Topics
- Animals
- Cell Line
- Coccidiostats
- Drug Resistance
- Female
- Fibroblasts
- Humans
- Mice
- Microscopy, Electron
- Mutation
- Nitriles
- Serial Passage
- Toxoplasma
- Triazines
