Article
A novel phenotype of an excision-repair mutant in Neurospora crassa: mutagen sensitivity of the mus-18 mutant is specific to UV.
Molecular & general genetics : MGG - 1 Aug 1991
Ishii C, Nakamura K, Inoue H
Abstract excerpt
A UV-sensitive mutant has been isolated from UV-mutagenized conidia of Neurospora crassa. The mutation responsible for the lesion was mapped in linkage group VL, proximal to the nucleolus organizer region. We designated the mutant mus-18. The sensitivity of the mus-18 mutant to UV-irradiation was not particularly high, being less than twice that of the wild-type strain. However, the frequency of mutations at the...
Topics
- 4-Nitroquinoline-1-oxide
- Alkylating Agents
- Chromosome Mapping
- DNA Damage
- DNA Repair
- DNA, Bacterial
- Dose-Response Relationship, Drug
- Dose-Response Relationship, Radiation
- Electrophoresis, Agar Gel
- Epistasis, Genetic