Article
Apo E variants in patients with type III hyperlipoproteinemia.
Atherosclerosis - 20 Dec 1996
Civeira F, Pocoví M, Cenarro A, Casao E, Vilella E, Joven J, González J, Garcia-Otín A L, Ordovás J M
Abstract excerpt
Type III hyperlipoproteinemia (HLP III) is characterized by the reduced catabolism and accumulation of chylomicron and very low density lipoprotein (VLDL) remnants. Most HLP III patients are homozygous for the apolipoprotein E2 (Cys112, Cys158) allele; however, several other mutations at this gen...
Topics
- Adolescent
- Adult
- Aged
- Apolipoproteins E
- DNA
- DNA Probes
- Female
- Genotype
- Humans
- Hyperlipoproteinemia Type III
- Isoelectric Focusing
- Male
- Middle Aged
- Phenotype
- Polymerase Chain Reaction
- Prevalence
- Spain