Article
Protected P-element termini suggest a role for inverted-repeat-binding protein in transposase-induced gap repair in Drosophila melanogaster.
Genetics - 1 Mar 1995
Staveley B E, Heslip T R, Hodgetts R B, Bell J B
Abstract excerpt
P-element transposition is thought to occur by a cut-and paste mechanism that generates a double-strand break at the donor site, the repair of which can lead to internally deleted elements. We have generated a series of both phenotypically stronger and weaker allelic derivatives of vg21, a vestigial mutant caused by a P-element insertion in the 5' region of the gene. Virtually all of the new alleles arose by...
Topics
- Alleles
- Animals
- Base Sequence
- DNA Repair
- DNA Transposable Elements
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Gene Deletion
- Molecular Sequence Data
- Nuclear Proteins