Article
Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae.
Genetics - 1 Mar 1995
Selva E M, New L, Crouse G F, Lahue R S
Abstract excerpt
A homeologous mitotic recombination assay was used to test the role of Saccharomyces cerevisiae mismatch repair genes PMS1, MSH2 and MSH3 on recombination fidelity. A homeologous gene pair consisting of S. cerevisiae SPT15 and its S. pombe homolog were present as a direct repeat on chromosome V, with the exogenous S. pombe sequences inserted either upstream or downstream of the endogenous S. cerevisiae gene. Each...
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