Article
Mismatch correction acts as a barrier to homeologous recombination in Saccharomyces cerevisiae.
Genetics - 1 Mar 1995
Selva E M, New L, Crouse G F, Lahue R S
Abstract excerpt
A homeologous mitotic recombination assay was used to test the role of Saccharomyces cerevisiae mismatch repair genes PMS1, MSH2 and MSH3 on recombination fidelity. A homeologous gene pair consisting of S. cerevisiae SPT15 and its S. pombe homolog were present as a direct repeat on chromosome V,...
Topics
- Base Sequence
- Chromosomes
- DNA Repair
- DNA-Binding Proteins
- Gene Deletion
- Mitosis
- Molecular Sequence Data
- Mutation
- Recombination, Genetic
- Saccharomyces cerevisiae
- Sequence Homology, Nucleic Acid
- TATA-Box Binding Protein
- Transcription Factors