Article
First evidence for homologous recombination-mediated large DNA inversion on the Bacillus subtilis 168 chromosome.
Bioscience, biotechnology, and biochemistry - 1 Oct 1994
Itaya M
Abstract excerpt
A Bacillus subtilis 168 strain carrying an inversion of about 1600 kb-long chromosomal DNA was isolated. Physical and genetic analyses demonstrated that the inversion was generated as a result of homologous recombination between two homologous sequences integrated at the met and leuB loci. This is the first clear evidence of a large stable chromosomal inversion induced by homologous recombination in B. subtilis.
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