Estimation of inbreeding coefficients from genotypic data on multiple alleles, and application to estimation of clonality in malaria parasites.

doi:10.1017/s0016672300033000

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Article

Estimation of inbreeding coefficients from genotypic data on multiple alleles, and application to estimation of clonality in malaria parasites.

Genetical research - 1 Feb 1995

Hill W G, Babiker H A, Ranford-Cartwright L C, Walliker D

Abstract excerpt

Methods for estimating probability of identity by descent (f) are derived for data on numbers of genotypes at single loci and at pairs of loci with many alleles at each locus. The methods are general, but are specifically applied to data on genotype frequencies in zygotes of the malaria parasite...

Topics

Algorithms
Alleles
Animals
Clone Cells
Gene Frequency
Genes, Protozoan
Genetic Linkage
Genotype
Germ Cells
Inbreeding
Likelihood Functions
Models, Genetic
Plasmodium falciparum
Tanzania
Zygote

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