Identical HLA class II alleles predispose to drug-triggered and idiopathic pemphigus vulgaris.

doi:10.2340/00015555751214

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Article

Identical HLA class II alleles predispose to drug-triggered and idiopathic pemphigus vulgaris.

Acta dermato-venereologica - 1 Jan 1995

Matzner Y, Erlich H A, Brautbar C, Sanilevitch A, Landau M, Brenner S, Friedmann A

Abstract excerpt

In pemphigus vulgaris, a dermatological autoimmune disease, specific human leukocyte antigen (HLA) class II alleles, DR4 (DRB1*0402) and DRw14 (DRB1*1401, in linkage disequilibrium with DQB1*0503), are thought to be susceptibility genes involved in the onset of the disease. We studied the HLA cla...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Autoimmune Diseases
Disease Susceptibility
Female
Genetic Linkage
HLA Antigens
HLA-DP Antigens
HLA-DP beta-Chains
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DR Serological Subtypes
HLA-DR4 Antigen
HLA-DRB1 Chains

Source

Open in PubMed

Identifiers

PMID: 7747528
DOI: 10.2340/00015555751214

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7747528-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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