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Article

Glycoprotein B of bovine herpesvirus-1 binds heparin.

Virology - 10 May 1995

Byrne K M, Horohov D W, Kousoulas K G

Abstract excerpt

Many members of the herpesvirus family have been shown to bind heparan sulfate on the surface of target cells. A previous report on bovine herpesvirus-1 (BHV-1) glycoprotein interactions indicated that only gC bound to heparin-agarose columns. In this report, we demonstrated that both gC and gB of wild-type BHV-1 bound to heparin-agarose columns and that gC-minus virus infectivity was inhibited by heparin.

Topics

Adsorption
Animals
Cattle
Cell Membrane
Cells, Cultured
Heparin
Herpesvirus 1, Bovine
Mutation
Protein Binding
Viral Envelope Proteins
Viral Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7747474
DOI: 10.1006/viro.1995.1248

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7747474-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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