Cellular proteins specifically bind to the 5'-noncoding region of hepatitis C virus RNA.

doi:10.1006/viro.1995.1204

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Article

Cellular proteins specifically bind to the 5'-noncoding region of hepatitis C virus RNA.

Virology - 20 Apr 1995

Yen J H, Chang S C, Hu C R, Chu S C, Lin S S, Hsieh Y S, Chang M F

Abstract excerpt

Hepatitis C virus (HCV) RNA contains a highly conserved 5'-noncoding region (5'NCR) which may be important in viral multiplication. To study the possible mechanisms of the cellular proteins involved in HCV replication and pathogenesis, a gel mobility shift assay and competition analysis were perf...

Topics

Animals
Base Sequence
Cell Extracts
Cell Line
Haplorhini
Hepacivirus
Humans
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Protein Biosynthesis
RNA, Viral
RNA-Binding Proteins
Ribonucleoproteins
Tumor Cells, Cultured
Ultraviolet Rays
Viral Core Proteins
Viral Proteins

Source

Open in PubMed

Identifiers

PMID: 7747444
DOI: 10.1006/viro.1995.1204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7747444-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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