Article
Cellular proteins specifically bind to the 5'-noncoding region of hepatitis C virus RNA.
Virology - 20 Apr 1995
Yen J H, Chang S C, Hu C R, Chu S C, Lin S S, Hsieh Y S, Chang M F
Abstract excerpt
Hepatitis C virus (HCV) RNA contains a highly conserved 5'-noncoding region (5'NCR) which may be important in viral multiplication. To study the possible mechanisms of the cellular proteins involved in HCV replication and pathogenesis, a gel mobility shift assay and competition analysis were performed with the HCV 5'NCR. Two specific complexes were formed between the 341-nucleotide RNA of the HCV 5'NCR and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
