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Article

MicroRNA-mediated interactions between host and hepatitis C virus

1 Jan 2016

Abstract excerpt

MicroRNAs (miRNAs) are small noncoding RNAs. More than 2500 mature miRNAs are detected in plants, animals and several types of viruses. Hepatitis C virus (HCV), which is a positive-sense, single-stranded RNA virus, does not encode viral miRNA. However, HCV infection alters the expression of host miRNAs, either in cell culture or in patients with liver disease progression, such as liver fibrosis, cirrhosis, and...

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PMID: 26819516
DOI: 10.3748/wjg.v22.i4.1487

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