Neurofibromatosis 1 and multiple sclerosis.

Abstract excerpt

Neurofibromatosis 1 is a common autosomal dominant disease that principally involves the skin and peripheral nervous system. The gene for the disorder has been located on chromosome 17q11.2 and there are three embedded genes within the neurofibrosis gene. One of these genes codes for oligodendrocyte-myelin glycoprotein, is found in the CNS during myelination, and may have a role in myelin formation. The case...

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