Article
The Caenorhabditis elegans spe-26 gene is necessary to form spermatids and encodes a protein similar to the actin-associated proteins kelch and scruin.
Genes & development - 1 May 1995
Varkey J P, Muhlrad P J, Minniti A N, Do B, Ward S
Abstract excerpt
Six independent mutations in the Caenorhabditis elegans spe-26 gene cause sterility in males and hermaphrodites by disrupting spermatogenesis. Spermatocytes in mutants with the most severe alleles fail to complete meiosis and do not form haploid spermatids. Instead, these spermatocytes arrest wit...
Topics
- Actins
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Carrier Proteins
- Chromosome Mapping
- Cytoskeletal Proteins
- Genes, Helminth
- Helminth Proteins
- Male
- Molecular Sequence Data
- Mutation
- Phenotype
- RNA, Helminth
- RNA, Messenger
- Sequence Analysis, DNA