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The Caenorhabditis elegans spe-26 gene is necessary to form spermatids and encodes a protein similar to the actin-associated proteins kelch and scruin.

Genes & development - 1 May 1995

Varkey J P, Muhlrad P J, Minniti A N, Do B, Ward S

Abstract excerpt

Six independent mutations in the Caenorhabditis elegans spe-26 gene cause sterility in males and hermaphrodites by disrupting spermatogenesis. Spermatocytes in mutants with the most severe alleles fail to complete meiosis and do not form haploid spermatids. Instead, these spermatocytes arrest with missegregated chromosomes and mislocalized actin filaments, endoplasmic reticulum and ribosomes. In spite of this...

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Identifiers

PMID: 7744249
DOI: 10.1101/gad.9.9.1074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Caenorhabditis elegans spe-26 gene is necessary to form spermatids and encodes a protein similar to the actin-associated proteins kelch and scruin.PMID 7744249Read ↗

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SPE-44 Implements Sperm Cell FateSemantic proximity Read ↗

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The Caenorhabditis elegans spe‐49 gene is required for fertilization and encodes a sperm‐specific transmembrane protein homologous to SPE‐42Semantic proximity Read ↗

Mutation of a putative sperm membrane protein in Caenorhabditis elegans prevents sperm differentiation but not its associated meiotic divisions.Semantic proximity Read ↗

A New Player in the Spermiogenesis Pathway of Caenorhabditis elegans.Semantic proximity Read ↗

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spe-12 encodes a sperm cell surface protein that promotes spermiogenesis in Caenorhabditis elegans.Semantic proximity Read ↗

A novel function for the presenilin family member spe-4: inhibition of spermatid activation in Caenorhabditis elegans.Semantic proximity Read ↗

spe-10 encodes a DHHC-CRD zinc-finger membrane protein required for endoplasmic reticulum/Golgi membrane morphogenesis during Caenorhabditis elegans spermatogenesis.Semantic proximity Read ↗

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