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Article

spe-10 encodes a DHHC-CRD zinc-finger membrane protein required for endoplasmic reticulum/Golgi membrane morphogenesis during Caenorhabditis elegans spermatogenesis.

Genetics - 1 Jan 2006

Gleason Elizabeth J, Lindsey Wesley C, Kroft Tim L, Singson Andrew W, L'hernault Steven W

Abstract excerpt

C. elegans spermatogenesis employs lysosome-related fibrous body-membranous organelles (FB-MOs) for transport of many cellular components. Previous work showed that spe-10 mutants contain FB-MOs that prematurely disassemble, resulting in defective transport of FB components into developing spermatids. Consequently, spe-10 spermatids are smaller than wild type and contain defective FB-MO derivatives. In this...

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Identifiers

PMID: 16143610
DOI: 10.1534/genetics.105.047340
PMCID: PMC1456142

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