Article
Genetic complementation of the immortal phenotype in group D cell lines by introduction of chromosome 7.
Japanese journal of cancer research : Gann - 1 Jan 1995
Ogata T, Oshimura M, Namba M, Fujii M, Oishi M, Ayusawa D
Abstract excerpt
Human immortal cell lines have been classified into at least four (A-D) genetic complementation groups by cell-cell hybrid analysis, i.e., a hybrid derived from different groups becomes mortal. Recently we have demonstrated that introduction of human chromosome 7 suppresses indefinite division po...
Topics
- Base Sequence
- Carcinoma, Hepatocellular
- Cell Death
- Cell Division
- Cell Line, Transformed
- Chromosomes, Human, Pair 7
- Fibroblasts
- Gene Transfer Techniques
- Genetic Complementation Test
- Humans
- Hybrid Cells
- Liver Neoplasms
- Molecular Sequence Data
- Phenotype
- Tumor Cells, Cultured