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Salmonella enterica serovar Typhimurium periplasmic superoxide dismutases SodCI and SodCII are required for protection against the phagocyte oxidative burst.

Infection and immunity - 1 Sept 2002

Sly Laura M, Guiney Donald G, Reiner Neil E

Abstract excerpt

Vitamin D(3) (1,25-dihydroxycholecalciferol) induced the phagocyte oxidative burst and intracellular killing of Salmonella enterica serovar Typhimurium in a phosphatidylinositol 3-kinase-dependent manner. The antimicrobial effect was more pronounced for Salmonella SodCI and SodCII mutants, confirming the role of the phagocyte oxidase in the vitamin D(3) effect. The results for an in vitro system with human THP-1...

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Identifiers

PMID: 12183590
DOI: 10.1128/IAI.70.9.5312-5315.2002
PMCID: PMC128279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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