Article
Heterogeneity of disease phenotype in monozygotic twins concordant for rheumatoid arthritis.
British journal of rheumatology - 1 Mar 1995
MacGregor A J, Bamber S, Carthy D, Vencovsky J, Mageed R A, Ollier W E, Silman A J
Abstract excerpt
The objective of the study was to investigate the genetic contribution to the clinical expression of rheumatoid arthritis (RA) by comparison of disease features in RA-concordant monozygotic (MZ) twin pairs. Fourteen RA-concordant MZ twin pairs recruited from a nation-wide study were examined to determine the degree of similarity in: (a) age of disease onset; (b) pattern of joint involvement; (c) pattern of...
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