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Article

Heterogeneity of disease phenotype in monozygotic twins concordant for rheumatoid arthritis.

British journal of rheumatology - 1 Mar 1995

MacGregor A J, Bamber S, Carthy D, Vencovsky J, Mageed R A, Ollier W E, Silman A J

Abstract excerpt

The objective of the study was to investigate the genetic contribution to the clinical expression of rheumatoid arthritis (RA) by comparison of disease features in RA-concordant monozygotic (MZ) twin pairs. Fourteen RA-concordant MZ twin pairs recruited from a nation-wide study were examined to determine the degree of similarity in: (a) age of disease onset; (b) pattern of joint involvement; (c) pattern of...

Topics

Age Factors
Aged
Arthritis, Rheumatoid
Female
Genetic Heterogeneity
Humans
Immunoglobulin M
Male
Middle Aged
Phenotype
Rheumatoid Factor
Twins, Monozygotic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7728394
DOI: 10.1093/rheumatology/34.3.215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7728394-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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