Article
On the Origin of Rheumatoid Arthritis: The Impact of Environment and Genes—A Population Based Twin Study
28 Feb 2013
Abstract excerpt
BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease with a complex origin. Previous studies have reported heritability estimates on RA at about 60%. Only 16% of the genetic background of the disease has been disclosed so far. The purpose of the present investigation was to provide an optimized estimate on the heritability of RA and to study the recurrence risk in a nationwide Caucasian twin population....
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