Article
Hutchinson-Gilford progeria types defined by differential binding of lectin DSA.
Biochimica et biophysica acta - 24 Apr 1995
Clark M A, Weiss A S
Abstract excerpt
Hutchinson-Gilford Progeria Syndrome (progeria) is an extremely rare childhood disorder characterized by precocious senility which presents features similar to those seen in human aging. We have previously described a consistent increase of the glycoprotein gp200 in progeria skin fibroblasts in vitro. Here we extend these glycosylation studies and present evidence for the existence of two types of progeria skin...
Topics
- Adolescent
- Carbohydrate Sequence
- Cells, Cultured
- Child
- Child, Preschool
- Female
- Fibroblasts
- Glycoproteins
- Humans
- Infant
- Lectins
- Male