Article
Insertion/deletion polymorphism in the angiotensin-converting enzyme gene and risk of restenosis after coronary angioplasty.
Lancet (London, England) - 22 Apr 1995
Samani N J, Martin D S, Brack M, Cullen J, Chauhan A, Lodwick D, Harley A, Swales J D, de Bono D P, Gershlick A H
Abstract excerpt
Early restenosis in over 30% of cases limits the benefits of percutaneous transluminal coronary angioplasty (PTCA). The mechanisms that underlie restenosis are uncertain, although experimental evidence suggests that the renin-angiotensin system is involved in the vascular response to angioplasty. An insertion(I)/deletion(D) polymorphism in the angiotensin-converting enzyme (ACE) gene, which influences plasma ACE...
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