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Article

Angiotensin-converting enzyme insertion/deletion polymorphism and risk of restenosis after directional coronary atherectomy followed by stent implantation.

Thrombosis and haemostasis - 1 Apr 2004

Canosi Umberto, Angelica Merlini Piera, Bernardi Francesco, Repetto Alessandra, Bramucci Ezio, Ferrario Maurizio, Angoli Luigi, Gnecchi Massimiliano, Ferraresi Paolo, Marchetti Giovanna, Tavazzi Luigi, Ardissino Diego

Abstract excerpt

The D allele of the insertion/deletion (I/D) polymorphism of the angiotensin I-converting enzyme (ACE) gene is associated with higher plasma and tissue ACE levels, which enhance the stimulus for neo-intimal hyperplasia. Plaque debulking before stenting reduces the plaque-related determinants of i...

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Source

Identifiers

PMID: 15045142
DOI: 10.1160/TH03-10-0619

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15045142-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Angiotensin-converting enzyme insertion/deletion polymorphism and risk of restenosis after directional coronary atherectomy followed by stent implantation.PMID 15045142Read ↗

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