Treatment of patients with familial defective apolipoprotein B-100 with pravastatin and gemfibrozil: a two-period cross-over study.

doi:10.1007/BF00577757

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Article

Treatment of patients with familial defective apolipoprotein B-100 with pravastatin and gemfibrozil: a two-period cross-over study.

The Clinical investigator - 1 Dec 1994

Hansen P S, Meinertz H, Gerdes L U, Klausen I C, Faergeman O

Abstract excerpt

Thirty patients with familial defective apolipoprotein B-100 were treated in a two-period (8 weeks each) cross-over study with pravastatin and gemfibrozil. Cholesterol, LDL cholesterol, and apo B were reduced by 20-25% (P < 10(-4)) by pravastatin and by 4-6% by gemfibrozil (pravastatin vs. gemfib...

Topics

Adult
Apolipoprotein B-100
Apolipoproteins B
Cross-Over Studies
Female
Gemfibrozil
Heterozygote
Humans
Male
Middle Aged
Mutation
Pravastatin
Statistics as Topic

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