Decreased resistance against in vitro oxidation of LDL from patients with familial defective apolipoprotein B-100.

doi:10.1161/01.atv.14.3.489

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Article

Decreased resistance against in vitro oxidation of LDL from patients with familial defective apolipoprotein B-100.

Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Mar 1994

Stalenhoef A F, Defesche J C, Kleinveld H A, Demacker P N, Kastelein J J

Abstract excerpt

Familial defective apolipoprotein B-100 (FDB) is caused by a mutation in the receptor-binding region of apolipoprotein B-100, the structural protein of the low-density lipoprotein (LDL) particle. We studied the effect of this mutation on the composition and susceptibility to oxidative modificatio...

Topics

Adult
Apolipoprotein B-100
Apolipoproteins B
Fatty Acids
Female
Humans
Lipoproteins, LDL
Male
Middle Aged
Mutation
Oxidation-Reduction
Vitamin E

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