Article
Efficacy and safety of once-daily vs twice-daily dosing with fluvastatin, a synthetic reductase inhibitor, in primary hypercholesterolemia.
Archives of internal medicine - 14 Nov 1994
Insull W, Black D, Dujovne C, Hosking J D, Hunninghake D, Keilson L, Knopp R, McKenney J, Stein E, Troendle A J
Abstract excerpt
BACKGROUND: Fluvastatin sodium is a new, entirely synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor that may be an effective lipid-lowering agent in patients whose hyperlipidemia does not respond to dietary therapy. We conducted a study to evaluate the effects of fluvastatin on lipoprotein levels in subjects with primary hypercholesterolemia and to compare the efficacy and safety of two...
Topics
- Adult
- Aged
- Apolipoproteins E
- Double-Blind Method
- Fatty Acids, Monounsaturated
- Female
- Fluvastatin
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Hypercholesterolemia