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Article

Pathogenicity of influenza A/Seal/Mass/1/80 virus mutants for mammalian species.

Archives of virology - 1 Jan 1995

Scheiblauer H, Kendal A P, Rott R

Abstract excerpt

Increases in infectiousness, neurotropism and virulence were found in a laboratory variant of influenza A/Seal/Massachussets/1/80 (H7N7) virus having a highly cleavable hemagglutinin. Sequential passage from host to host further increased pathogenicity of the H7N7 virus in mice, ferrets and rats.

Topics

Animals
Brain
Female
Ferrets
Hemagglutinins, Viral
Influenza A virus
Lung
Mice
Mutation
Orthomyxoviridae Infections
Rats
Rats, Inbred Lew
Seals, Earless

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serial Passage

Virulence

Virus Replication

Source

Identifiers

PMID: 7710359
DOI: 10.1007/BF01309867

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7710359-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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