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Article

Different roles of bases within the integration signal sequence of human immunodeficiency virus type 1 in vitro.

Journal of virology - 1 May 1995

Yoshinaga T, Fujiwara T

Abstract excerpt

To investigate the roles of bases near the tips of each strand of the long terminal repeat of the human immunodeficiency virus type 1 in the integration reaction, we examined the efficiencies of both binding and integration activities of staggered-ended substrates and mismatched mutant substrates by the integration assay and the UV cross-linking assay. Our results suggest that some bases of the human...

Topics

Base Sequence
Binding Sites
Cross-Linking Reagents
DNA, Viral
HIV Long Terminal Repeat
HIV-1
Humans
In Vitro Techniques
Molecular Sequence Data
Mutation
RNA, Viral
Ultraviolet Rays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virus Integration

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Identifiers

PMID: 7707558
DOI: 10.1128/JVI.69.5.3233-3236.1995
PMCID: PMC189032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7707558-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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