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Widespread activation of antisense transcription of the host genome during herpes simplex virus 1 infection

31 Oct 2017

Abstract excerpt

BACKGROUND: Herpesviruses can infect a wide range of animal species. Herpes simplex virus 1 (HSV-1) is one of the eight herpesviruses that can infect humans and is prevalent worldwide. Herpesviruses have evolved multiple ways to adapt the infected cells to their needs, but knowledge about these transcriptional and post-transcriptional modifications is sparse. RESULTS: Here, we show that HSV-1 induces the...

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PMID: 29089033
DOI: 10.1186/s13059-017-1329-5

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