Article
Mechanism of Interferon Beta-Induced Squamous Differentiation and Programmed Cell Death in Human Non--Small--Cell Lung Cancer Cell Lines
1 Feb 1995
Abstract excerpt
BACKGROUND: Non-small-cell lung cancer (NSCLC) is one of the leading causes of cancer-related mortality due largely to the failure of systemic chemotherapy. Thus, new therapeutic paradigms involving the manipulation of normal physiologic growth-regulatory mechanisms, such as terminal cellular differentiation or programmed cell death, are being explored. Interferons may function as antineoplastic agents, in part...
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