Article
A maternal product of the Punch locus of Drosophila melanogaster is required for precellular blastoderm nuclear divisions.
Journal of cell science - 1 Dec 1994
Chen X, Reynolds E R, Ranganayakulu G, O'Donnell J M
Abstract excerpt
The Punch locus of Drosophila melanogaster encodes the pteridine biosynthesis enzyme guanosine triphosphate cyclohydrolase. One class of Punch mutants is defective for a maternal function that results in embryonic death. We demonstrate here that the embryos exhibit nuclear division defects during...
Topics
- Animals
- Blastoderm
- Cell Division
- Cell Nucleus
- Drosophila melanogaster
- Female
- GTP Cyclohydrolase
- Genes, Insect
- Hypoxanthines
- Microscopy, Fluorescence
- Microscopy, Immunoelectron
- Microtubules
- Mutation
- Nuclear Envelope
- Oogenesis
- Ovum
- Phenotype
- Pteridines