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Article

A maternal product of the Punch locus of Drosophila melanogaster is required for precellular blastoderm nuclear divisions.

Journal of cell science - 1 Dec 1994

Chen X, Reynolds E R, Ranganayakulu G, O'Donnell J M

Abstract excerpt

The Punch locus of Drosophila melanogaster encodes the pteridine biosynthesis enzyme guanosine triphosphate cyclohydrolase. One class of Punch mutants is defective for a maternal function that results in embryonic death. We demonstrate here that the embryos exhibit nuclear division defects during the precellular blastoderm stage of development. These defects include abnormal nuclear distribution, mitotic...

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PMID: 7706401
DOI: 10.1242/jcs.107.12.3501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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