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Article

Prolonged P300 latency in a neuropsychiatric population with the D2 dopamine receptor A1 allele.

Pharmacogenetics - 1 Dec 1994

Blum K, Braverman E R, Dinardo M J, Wood R C, Sheridan P J

Abstract excerpt

The role of the dopaminergic system in P300 has been implicated and previous studies have suggested the presence of a heritable component in the genesis of P300 or P3, a late positive component of the event-related potential. In the present investigation, 155 Caucasian male and female diagnosed neuropsychiatrically-ill patients with and without comorbid drug and alcohol abuse/dependence were genotyped for the...

Topics

Adult
Aged
Alleles
Electrophysiology
Evoked Potentials, Auditory
Female
Genetic Markers
Genotype
Humans
Male
Mental Disorders
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Restriction Fragment Length

Receptors, Dopamine D2

Substance-Related Disorders

Source

Identifiers

PMID: 7704037
DOI: 10.1097/00008571-199412000-00004

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7704037-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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